GPCR – DRUG TARGETS - An Exclusive Market Insight Report from RI Technologies

FOR IMMEDIATE RELEASE
Hyderabad, Andhra Pradesh, India, Republic of (Free-Press-Release.com) December 6, 2011 --

November 9, 2011 - RI Technologies’ (www.researchimpact.com) market insight report on G-Protein Coupled Receptors (GPCR) covers the types of GPCR Families and the various ligands targeting GPCR. The GPCR families covered include Rhodopsin, Secretin, Glutamate and Other. The Ligands targeting GPCRs include Peptides or Proteins, Biogenic Amines, Lipids and Other. The report provides market analysis of each of the Families and ligands targeting GPCRs by their respective categories. The study includes estimations and predictions for the total global GPCR – Drug targets market and also key regional markets that include North America, Europe, Japan, Asia-Pacific (excluding Japan) and Rest of World. Estimations and predictions (2005-2015) are illustrated graphically with 80 exhibits. Business profiles of 13 major companies engaged in developing GPCR targeted drugs, GPCR cell lines and GPCR Assays are discussed in the report. The report serves as a guide to global GPCR –Drug Targets industry, covering more than 130 companies that are engaged in the development of GPCR Targeted Drugs, GPCR Assays Information related to recent product releases, Assay developments, partnerships, collaborations, and mergers and acquisitions is also covered in the report.

G-Proteins form a link between the cell surface receptors and the intracellular events by interacting with GTP. The phenomenon in which external stimuli bring about an expanding cascade of intracellular events culminating in specific cellular responses is called signal transduction. The complex involved in this phenomenon consists of GPCR and G-Protein. This assembly is the most diverse among the cell surface receptors.

Future progress may relate discoveries to the development of new medicines. At present the development of drugs is centered on the discovery of chemicals that influence the ability of the ligands to bind with the G-Protein Coupled Receptor or GPCR. This will either accelerate or inhibit the cellular process. In the in-depth studies pertaining to the G-Protein Coupled Receptor family, the role of chemical biology has been significant since the beginning. This is because the majority of the vital group of targets is for improvement in therapeutics. These receptors are defined by a common structural feature which is comprised of seven hydrophobic trans-membrane segments. These proteins are also known as 7 TM, seven trans-membranes or serpentine receptors because in all cases the signaling through heterotrimeric G-Proteins is not exhibited.

GPCRs together with G-Proteins are known to have a very important role in physiology and diseases including diseases of the sense organs, digestive tract, endocrine system, and respiratory system and their processes. GPCRs are known to be attractive drug targets for several reasons. Firstly the location of the GPCRs on the cell surface makes them easy targets for the drugs. In addition, GPCRs are generally present everywhere as they play an important role in almost every system of the human body. As the human genome project is completed unknown functions of many of the genes expressing into GPCRs can be unraveled and thereby making them potential drug targets proteins in drug development.


About RI Technologies

RI Technologies, established in 2006, is a premier source of market research on the Biotechnology & Healthcare sector with exclusive focus on product segments, global and regional market analysis, technology trends, industry outlook, competitor profiles, corporate directory and patents information. The company believes in pure research that will trigger action for immediate customer needs rather than plain reporting of data. The dedicated team works 24/7 to deliver unique reports that are of immense value to investment banks, companies, management consultants, trade associations, corporate executives, business analysts, libraries, universities, and business schools. The company's reports provide strategic information tools to the manufacturers, retailers, distributors, and suppliers that will help them to probe into and support critical business decisions. RI Technologies believes in broadening the value of market research obtained through several dedicated streams of information. The strategic market information tables, graphically represented, will aid companies' research needs and help in forecasting, and gearing up to the future. Emphasis is on factual insights and forecasts with maximum global coverage. The company strives to provide market insight reports that empower customers with enlightening critical business information.

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