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New Knock-out Rat, Knock-in Rat, Rat Model Generation Services

February 21,2013


Applied StemCell Inc. (ASC) proudly announces that we now provide a service for the generation of rat model services. This service was launched on 12/1/2012.

Rats are prominent experimental animals in various fields of biomedical research including cardiovascular diseases, cancer research, and industrial toxicology and pharmacology studies. The laboratory rat (R. norvegicus) is more robust than mice for physiological and behavioral studies, and has historically been the model of choice for these applications. However, due to the of the lack of transgenic rats mice were the eminent research animal over the last decades.

The recent availability of rat embryonic stem cells now allows us to make transgenic rats and our line of knock-out rats, and knock-in rats. The technology is similar to that used for gene-targeting in mice, however the culture of rat embryonic stem cells require special conditions. Also, only few rat embryonic stem cell lines have been tested for successful germ-line transmission as this test is time-consuming and expensive.

Our competence in gene-targeting vector design coupled with our expertise in culturing rat embryonic stem cells allows us to offer a high-quality knock-in, and knock-out rat service. Please contact us to discuss your project with us so you can get your transgenic rats as soon as possible.

Applied StemCell, Inc. is a leading provider in stem cell products and services including MEF Feeder Cells, Transgenic Knock-in Mice, ROSA26 Embryos, Teratoma Formation Services, Human Primary Cells, Stem Cell Characterization, Stem Cell Differentiation and Stem Cell Generation. We strive to improve while expanding our technologies and product lines to meet the increasing requirements of biomedical community. Applied StemCell always welcomes your comments, suggestions and ideas.



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Applied StemCell, Inc.

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