Treatment of ovarian cancer

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Most women with ovarian cancer will have surgery at some point during the course of their disease, and each surgery has different goals...
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January 10, 2005 (Press Release) -- Treatment of ovarian cancer: Initial surgery (for diagnosis and treatment)

Most women with ovarian cancer will have surgery at some point during the course of their disease, and each surgery has different goals:

Initial surgery (for diagnosis and treatment)

– Initial surgery: technique

· Usually performed by laparotomy, a surgery that involves a vertical (up and down) incision in the abdomen that is large enough to allow the surgeon to look inside the body and remove cancerous tissue

· Sometimes includes debulking, which is described as removal of all visible cancer. In addition, it also involves removal of one or both ovaries and fallopian tubes (salpingo-oopharectomy) and often the removal of the uterus (hysterectomy). It is important that a gynecologic oncologist is the leader of the surgical team, as prognosis is closely related to how much of the cancer cannot be removed during surgery.

– Goal: diagnosis

· Obtain an accurate surgical diagnosis, which is crucial for planning an appropriate treatment strategy

· Determine how far the cancer has spread (“staging” the cancer)

· Obtain a biopsy sample to analyze the cellular characteristics of the cancer

– Goal: treatment

· “Debulking” to remove as much of the cancer tissue as possible

· Optimal debulking of the tumor in women with bulky disease can improve outcome

“Second-look” surgery is a follow-up for women whose cancer responds to chemotherapy. [Not performed routinely]

– Second-look surgery: techniques

· Laparotomy

· Laparoscopy

– Surgery using fiberoptic scopes and tubes

– Less invasive (can be performed through small [ ≤ 1 inch] incisions in the abdomen)

– Goal: diagnosis

· To investigate whether any cancer remains in the abdominal cavity and will require further treatment

– The role of second-look surgery in disease management is evolving, and this technique might be replaced by other, less-invasive assessment methods

Additional debulking surgery

– Goal: treatment

· To reduce cancer symptoms and improve the effects of chemotherapy

Surgery for recurrent ovarian cancer

– To remove measurable disease after a reasonable disease-free interval

– To remove bowel or ureteral obstruction

http://www.ovarian.org/


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Treatment of ovarian cancer

http://www.ovarian.org/

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