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News Archive > 2007 > Mar > 23
For those diagnosed with mesothelioma, an asbestos-related cancer of the lining of the lung (pleura) or the lining of the abdominal cavity (peritoneum), finding a credible source of information...
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March 23, 2007 (Press Release) -- What is Mesothelioma?
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The National Cancer Institute states that: "Malignant mesothelioma, a rare form of cancer, is a disease in which cancer (malignant) cells are found in the sac lining the chest (the pleura), the lining of the abdominal cavity (the peritoneum) or the lining around the heart (the pericardium)."

The main risk factor for mesothelioma cancer is asbestos exposure. Almost all cases of mesothelioma cancer can be linked to asbestos exposure. When people inhale asbestos fibers, they stick to the mucus in the air passages like the nose and throat. If they are not coughed up, the fibers can travel to the ends of the small airways and penetrate into the lung and chest wall. These fibers may then directly injure cells of the chest wall, and eventually cause mesothelioma cancer. This is called pleural mesothelioma.

People may also cough up and swallow asbestos fibers, which can cause mesothelioma cancer in the abdomen. This is called peritoneal mesothelioma.Researchers are still studying exactly how asbestos causes cells to develop into mesothelioma cancer. Asbestos fibers may damage a person's DNA, causing cells to grow uncontrollably.


Pleural Mesothelioma
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Pleural mesothelioma is the most common type of mesothelioma, accounting for 75% of all cases. The disease develops when people breathe in asbestos fibers. The fibers travel to the ends of small air passages in the lungs and damage the pleura. The pleura is the layer of tissue that lines the chest cavity and helps to protect organs.

Asbestos fibers damage the pleura by causing inflammation and scarring. Usually with pleural mesothelioma, the tumor appears in only one lung, often the right one. Cells become abnormal and grow out of control. Over time, pleural mesothelioma can break through the pleura and spread into chest wall or into the abdomen.


Peritoneal Mesothelioma
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Peritoneal mesothelioma, a form of cancer, accounts for only 10% - 20% of all cases with tumors typically growing in the abdomen. Peritoneal mesothelioma develops when people cough up and then swallow asbestos fibers thereby causing damage to the peritoneum. The peritoneum is the layer of tissue that lines the abdomen to protect organs.

Similar to pleural mesothelioma, asbestos fibers damage the peritoneum by causing inflammation and scarring. Cells become abnormal and grow out of control. Over time, peritoneal mesothelioma may break through the abdominal wall and invade organs like the lungs, heart, stomach, and liver. Peritoneal mesothelioma can even attach itself to blood vessels, the esophagus, or intestines, making it hard or even impossible to remove the cancer surgically.

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