Dr Ira L Shapira announces that early minimally invasive removal of wisdom teeth may provide vaccine against aging. 
United States of America (Press Release) November 25, 2007 --
Researchers in Madison, Wisconsin and Japan have recently announces the ability to turn
adult skin cells into stem cells capable of duplicating any tissue in the body. Dr Ira L Shapira a Gurnee, Illinois dentist who holds several patents on methods and devices for collection of bone marrow and stem cells predicts that this will lead into a vaccine against aging. This will not happen from typical adult stem cells but rather from stem cells derived at an early age from the patient. The best known method of stem cell collection from umbilical cords.The ability for stem cell researchers to be unrestricted by the current funding disasters should return The US to a position of prominence in Stem Cell research.
When Dolly the sheep was cloned she underwent premature aging and at two years old was physiologically the same age as her mother. This is because the Telomeres, a part of the DNA that control aging shortens as patient’s age. Collection of young healthy stem cells at an early age would assure that the Stem Cells have DNA in which the Telomeres have not shortened. These cells can be obtained from umbilical cord b;ood but they can also be obtained from the early developing wisdom teeth.
It has been shown that when Stem Cells are placed in the body they travel to all body organs. Collection of stem cells during minimally invasive removal of wisdom teeth would provide several benefits. The wisdom teeth at 10-12 years of age are positioned just under the gum tissue and can be removed easily with the instrumentation Dr Shapira designed with a minimal amount of surgery, pain or discomfort. A very tiny opening would allow the oral surgeon or pedodontist to easily remove the tooth before it is calcified and simultaneously collect stem cells from all germ layers. This would include the tissues that eventually would become enamel, dentin, the periodontal ligament, the dental pulp and the blood vessels and nerveis in the pulp. Because of the young age the Telomeres on the DNA would still be long and with minimal manipulation would be a perfect match for any tissue in the body of the donor. Unlike using skin cells only a minimum amount of manipulation would be necessary and Telomeres would be Intact.
This will change the field of oral surgery where currently fully developed teeth are removed from the jaws in an extensive surgical procedures that often requires removal of bone and sectioning of calcified teeth with associated morbidity. The early removal would allow the soft uncalcified tooth to be removed with minimal surgery thru a small opening via suctioning and a small cutting tool. This could be done very quickly with minimal associated morbidity.
Dr Shapira envisions these same tools and techniques being used to collect bone marrow from the sternum, calvarium as well as the hips with greater ease and less pain than conventional methods. The current method of bone marrow collection is crude compared to what we expect in the future. Collection of bone marrow from the sternum instead of the hip could produce a major reduction in pain for the recipient.
Dr Shapira is looking for partners to help him bring this work forward. The changes in the field of oral surgery alone will make this a profitable venture but the implications for increasing longevity is where the real excitement lies.
Dr Shapira is best known for his work in Dental Sleep Medicine and treating sleep apnea utilizing comfortable oral appliances as CPAP Alternatives. He is founder of I HATE CPAP LLC and www.ihatecpap.com a informational service for patients seeking alternatives to cpap and for dentists looking to promote their practice of Dental Sleep Medicine. He is a former Asst Professor at Rush Medical School, A Dipomate of the American Board of Dental Sleep Medicine, A Diplomate of the Academy of Pain Management and a Fellow and Regent of ICCMO. He teaches course to dentists on treating sleep apnea with oral appliances.
adult skin cells into stem cells capable of duplicating any tissue in the body. Dr Ira L Shapira a Gurnee, Illinois dentist who holds several patents on methods and devices for collection of bone marrow and stem cells predicts that this will lead into a vaccine against aging. This will not happen from typical adult stem cells but rather from stem cells derived at an early age from the patient. The best known method of stem cell collection from umbilical cords.The ability for stem cell researchers to be unrestricted by the current funding disasters should return The US to a position of prominence in Stem Cell research.
When Dolly the sheep was cloned she underwent premature aging and at two years old was physiologically the same age as her mother. This is because the Telomeres, a part of the DNA that control aging shortens as patient’s age. Collection of young healthy stem cells at an early age would assure that the Stem Cells have DNA in which the Telomeres have not shortened. These cells can be obtained from umbilical cord b;ood but they can also be obtained from the early developing wisdom teeth.
It has been shown that when Stem Cells are placed in the body they travel to all body organs. Collection of stem cells during minimally invasive removal of wisdom teeth would provide several benefits. The wisdom teeth at 10-12 years of age are positioned just under the gum tissue and can be removed easily with the instrumentation Dr Shapira designed with a minimal amount of surgery, pain or discomfort. A very tiny opening would allow the oral surgeon or pedodontist to easily remove the tooth before it is calcified and simultaneously collect stem cells from all germ layers. This would include the tissues that eventually would become enamel, dentin, the periodontal ligament, the dental pulp and the blood vessels and nerveis in the pulp. Because of the young age the Telomeres on the DNA would still be long and with minimal manipulation would be a perfect match for any tissue in the body of the donor. Unlike using skin cells only a minimum amount of manipulation would be necessary and Telomeres would be Intact.
This will change the field of oral surgery where currently fully developed teeth are removed from the jaws in an extensive surgical procedures that often requires removal of bone and sectioning of calcified teeth with associated morbidity. The early removal would allow the soft uncalcified tooth to be removed with minimal surgery thru a small opening via suctioning and a small cutting tool. This could be done very quickly with minimal associated morbidity.
Dr Shapira envisions these same tools and techniques being used to collect bone marrow from the sternum, calvarium as well as the hips with greater ease and less pain than conventional methods. The current method of bone marrow collection is crude compared to what we expect in the future. Collection of bone marrow from the sternum instead of the hip could produce a major reduction in pain for the recipient.
Dr Shapira is looking for partners to help him bring this work forward. The changes in the field of oral surgery alone will make this a profitable venture but the implications for increasing longevity is where the real excitement lies.
Dr Shapira is best known for his work in Dental Sleep Medicine and treating sleep apnea utilizing comfortable oral appliances as CPAP Alternatives. He is founder of I HATE CPAP LLC and www.ihatecpap.com a informational service for patients seeking alternatives to cpap and for dentists looking to promote their practice of Dental Sleep Medicine. He is a former Asst Professor at Rush Medical School, A Dipomate of the American Board of Dental Sleep Medicine, A Diplomate of the Academy of Pain Management and a Fellow and Regent of ICCMO. He teaches course to dentists on treating sleep apnea with oral appliances.
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