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(Free-Press-Release.com) July 21, 2009 -- Broad-spectrum antibiotic is antibiotic with activity against a wide range of disease-causing bacteria. It is also means that it acts against both Gram-positive and Gram-negative bacteria. This is in contrast to a narrow-spectrum antibiotic which is effective against only specific families of bacteria. A good example of a widely used broad-spectrum antibiotic is levofloxacin.
Uses
Broad-spectrum antibiotic is basicly used in the following medical situations:

Empirically prior to identifying the causative bacteria when there is a wide differential and potentially serious illness would result in delay of treatment. This occurs, for example, in meningitis, where the patient can become so ill that he could die within hours if broad-spectrum antibiotic is not initiated.
For drug resistant bacterias that doesn't responds to other, more narrow-spectrum antibiotics.
In super-infections where there are multiple types of bacteria causing illness, thus warranting either a broad-spectrum antibiotic or combination of manyantibiotic therapy.

There has been a common situations of broad-spectrum antibiotic agents in treatment of community acquired infections without attempting to culture or otherwise identify the causative bacteria. In certain situations, broad-spectrum antibiotic is absolutely necessary because if the disease is not defined (just can not identify what triggered, for example, meningitis, or a certain type of pneumonia), use of broad spectrum antibiotic is likely to be effective. Over the years, this practice has contributed to the emergence of more drug resistant strains of bacteria, necessitating the development of latest generations of broad-spectrum antibiotics.
Ideally, the spectrum should be "narrowed down" by identifying the causative agent of an infection, and then replacing the broad-spectrum antibiotic with an appropriate narrower-spectrum antibiotic. This is believed to limit the development of antibiotic resistance, although evidence for this practice is unclear.
Examples
In medicine:
amoxycillin
levofloxacin, gatifloxacin, moxifloxacin
Others:
streptomycin
tetracycline
chloramphenicol
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